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Vertex Pharmaceuticals Incorporated (VRTX)

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267,73-0,45 (-0,17%)
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  • A
    Alex
    Onconova Therapeutics, Inc.
    to Dorian, Ni3, bullfight 2020, Mihir, and all my other bull gang friends from last November: this pop is my exit for the time, and what a rollercoaster ride it's been. looking to move money into $VRTX pharmaceuticals in the meantime, will reevaluate onconova when more has been reported on ON12330. good luck to you all, hope to see you around on the other boards making fat gains! until then, o7
  • V
    VirginiaLova
    $EDIT conversation
    CRISPR TX & VERTEX TX — big news today. Amazed at their process in curing sickle cell. $CRSP $VRTX $NTLA $Pfe
  • G
    GoldCoinCollector
    $PTI conversation
    $PTI Logic 101, with PTI trading near "CASH" with NO debt, & NO warrants. PTI has the WORLD's 1st EVER:
    "Proteostasis Therapeutics and CF Europe Announce Completion of Patient Enrollment for CHOICES, the First-Ever Personalized Medicine-Based Study in Cystic Fibrosis"
    https://ir.proteostasis.com/news-releases/news-release-details/proteostasis-therapeutics-and-cf-europe-announce-completion

    PTI has the WORLD's only AMPLIFIER modulator that WORKS:
    http://www.proteostasis.com/modulators-and-pipeline/

    Will $VRTX make a run for PTI to have a COMPLETE MONOPOLY with NO potential competition... ?
    Proteostasis Therapeutics and CF Europe Announce Completion of Patient Enrollment for CHOICES, the First-Ever Personalized Medicine-Based Study in Cystic Fibrosis | Proteostasis Therapeutics, Inc.
    ir.proteostasis.com
  • G
    GoldCoinCollector
    $PTI conversation
    PTI yep agree, $VRTX would basically have a MONOPOLY throughout the WORLD if they acquired PTI... PTI has the WORLD's 2nd highest ppFEV1 (not too far off from VRTX), with $ABBV the WORLD's 3rd highest....
  • P
    Pancakes
    $PTI conversation
    $PTI or $VRTX top contenders:
    01 July 2020
    COVID-19 meets Cystic Fibrosis: for better or worse?

    "We hypothesise that CFTR modulator therapy might also confer additional benefit to patients with severe respiratory problems due to COVID-19 infection "

    "...CFTR modulator therapy given to people with CF helps to restore cellular function, increases airway hydration, reduces oxidative stress, and down-regulates activation of the NLRP3 inflammasome"

    "The influence of CFTR in non-CF respiratory disease is intriguing and relatively poorly understood."

    "Carriers of the (commonest by far) Phe508del mutation found in over 70% of patients, have also been reported as having an increased risk of developing chronic bronchitis and bronchiectasis"

    "The role of CFTR in COVID-19 needs further elucidation in patients without CF."

    "We suggest that clinical trials of modern CF drugs should be explored in those infected by this new virus."

    ONLY 2 biotechs in the world PTI or VRTX have FEV1 over 8%.
  • B
    Bear
    $SRNE conversation
    $srne
    Who is with me to buy more at $10
    Who is with me to see it $15
    Who is with me to pump at $20
    Who will hold at $25
    Who is with me to sell above $30
    Inviting my friends from $tvix $uvxy $tsla $amzn $aapl $vrtx $mrna $nvax
    $SRNE is the stock market coming few weeks
  • P
    Pancakes
    $PTI conversation
    Triplet FEV1 best RESULTS reported so far:
    #1 $VRTX Triplet FEV1 believe 12% to 13%?

    #2 $PTI Triplet FEV1 believe 8%+ (?) NOTE upcoming "The readout will also represent the first look at the triplet data beyond 28 days, which unlike the doublet, kept demonstrating an increased benefit in ppFEV1. “We think a trial double in length of eight weeks will provide more context on the amplifier's potential. Additionally, we believe there is a lower bar for efficacy for the ultra-rate mutation population (as patients are ineligible for all approved modulators), and results could help explain how many patients show some level of benefit,”

    #3 $ABBV 3% Triplet FEV1
  • P
    Pancakes
    $PTI conversation
    $PTI early Christmas gift is welcomed:
    https://seekingalpha.com/news/3578955-proteostasis-therapeutics-ptiminus-129-potential-covidminus-19-candidate

    PTI or $VRTX the only 2 biotechs in the world with the modulator drugs w/ meaningful LUNG FUNCTION benefits:

    01 July 2020
    COVID-19 meets Cystic Fibrosis: for better or worse?

    "We hypothesise that CFTR modulator therapy might also confer additional benefit to patients with severe respiratory problems due to COVID-19 infection "

    "We suggest that clinical trials of modern CF drugs should be explored in those infected by this new virus."
    Proteostasis Therapeutics (NASDAQ:PTI) is up 21% premarket after announcing results from in vitro studies evaluating the use of PTI-129 as a treatment for COVID-19.PTI-129 is a pre-clinical, oral small molecule originally designed to treat protein mi
    Proteostasis Therapeutics (NASDAQ:PTI) is up 21% premarket after announcing results from in vitro studies evaluating the use of PTI-129 as a treatment for COVID-19.PTI-129 is a pre-clinical, oral small molecule originally designed to treat protein mi
    seekingalpha.com
  • V
    VirginiaLova
    $CRSP conversation
    Excited about the Suntrust upgrade. The analyst is a medical doctor. The Car - T program, as she noted, has not been priced into the stock. Her $140 target is low. Crsp, per Ceo, uses healthy donor cells, then does the edits to those cells using Crispr/ Cas9. The cancer treatments are then available “off the shelf” to be delivered to patients. This is critical for those with illness who need instant treatment. $CRSP wholly owns the Car-t program. $VRTX is partnered on most of the other developmental programs, including DMD. At any rate, the analyst from Suntrust is giving a price target, that when hit will be raised. I think the other analysts will be raising price targets soon too.
  • V
    VirginiaLova
    $CRSP conversation
    Crispr Therapeutics initiated with a Buy at SunTrust SunTrust CRSP
    Crispr Therapeutics initiated with a Buy at SunTrust SunTrust CRSP
    thefly.com
  • h
    highreturn2020
    $PTI conversation
    Posted on S.T. $VRTX lost any and all respect for your management team. Frankly, out right criminal:
    https://www.express.co.uk/news/uk/1106695/cystic-fibrosis-us-firm-orkambi-out-of-date-drug

    READ the most research report on PTI from January, with the author (brilliant thinking) updating in about 2 weeks based on a comment in S.T.
    https://www.reddit.com/r/Biotechplays/comments/eldsvx/pti_super_bull_thesis_my_top_20202021_pick_part_3/
    US GIANT Vertex has admitted destroying thousands of packets of a life-saving cystic fibrosis drug after they went out of date.
    US GIANT Vertex has admitted destroying thousands of packets of a life-saving cystic fibrosis drug after they went out of date.
    www.express.co.uk
  • s
    sailingseason
    Sorrento Therapeutics, Inc.
    $MBRX up 60% on COVID-19 news, look @ the Volume! $PTI all eyes, milestones in Aug, w/ 400% upside potential... SRNE $ALT $INO why the drop??? PTI could be huge the next $VRTX
  • t
    thirdmeinvestor
    $VRTX conversation
    $VRTX and $BMRN stocks are downgraded to equal-weight from overweight by Morgan Stanley. Biotech analyst at MS is good, but very conservative in their rating. Their target price is 300. If I have to guess, we can reach 350 by January.
  • s
    smartmoneynd
    $VRTX conversation
    Posted on S.T. 6m
    $VRTX new 52 week high, w/ $80 billion market cap. Yet,
    $PTI is a close second to VRTX in FEV1 lung function, coupled w/ the fact PTI has the only Amplifier in the clinic:
    Nesolicaftor (PTI-428), a first in class cystic fibrosis transmembrane conductance regulator (CFTR) amplifier, in CF patients.

    Yes, we are scratching our head with PTI trading:
    - Near CASH.
    - NO debt.
    - NO warrants out there.
  • V
    VirginiaLova
    $VRTX conversation
    HUGE NEWS IN EARNINGS RELEASE FOR $CRSP. $CRSP $VRTX — CRISPR CEO “We are now progressing five cell therapy clinical trials in parallel targeting hemoglobinopathies and various cancers” and they have enrolled more patients in the CTX001 trials
  • T
    Tad
    $ARWR conversation
    from twitter: 43s
    $VRTX Citi boosts PT to $325. 2020 guidance is for $5.3B to $5.6B of product sales. Makes me think of mere $3B market cap for $ARWR and what will happen if/when they report POC in CF (and opens door to other lung indications)...

    know what you own
  • K
    Kim
    $SRPT conversation
    FromSY investing:
    Cantor 2020 #biotech outlook

    Top picks:
    - Large-cap: $VRTX $AMGN
    - Mid-cap: $SRPT $ALNY
    - Small-cap: $TGTX $ICPT $GBT $AGIO
    - Favorite binary: $MYOK
  • A
    Arrowhead500
    $VRTX pipeline update: AAT ph2 study enrollment paused. The corona
  • T
    Thirdmeinvestor
    $VRTX conversation
    $VRTX made to the list of [Barron’s 100 Most Sustainable Companies] (= Barrons' Cover story). Only a few biotech companies belong to the group.
  • V
    VirginiaLova
    $CRSP conversation
    Since receiving a landmark treatment with the gene-editing tool CRISPR, a sickle cell patient has the strength to care for herself and her children — while navigating the pandemic.
    Since receiving a landmark treatment with the gene-editing tool CRISPR, a sickle cell patient has the strength to care for herself and her children — while navigating the pandemic.
    www.npr.org
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